The Next Generation Single-Use Bioreactor

Nucleo is a complete single-use solution for a wide range of cell culture applications, specifically developed and marketed for the biotech industry. Nucleo offers a complete range of single-use bioreactors, associated accessories and dedicated services in optimization of processes.



Together For Better
The Nucleo bioreactor utilizes both expertise from ATMI LifeSciences in ultra-pure bio-film/bags and disposable mixing technologies, and the Biolaffite Division of Pierre Guerin in fermentation and automated systems.

Description
The Nucleo single-use bioreactor was developed to provide a complete turn-key solution to cell culturists as a ‘next generation’ alternative to stainless steel classical bioreactors and existing disposable bioreactors, without need for extended validations.

The Nucleo disposable bioreactor represents the state of the art response to the evolution of biotech processes. It is perfectly suited to laboratory environments, process development centers, clinical material supply and flexible GMP manufacturing.

This innovative single-use bioreactor is based on the patented ATMI Pad-drive™ single-use mixing technology, providing optimal mixing efficiency, drastically reduced shear stress, as well as superior oxygen transfer rates created through the use of a unique dynamic sparger.

Nucleo offers a complete range of standard vessel sizes ranging from 25 to 600 liters, associated accessories and dedicated services. Vessels up to 1200 liters will be available in the near future.

Benefits
The ‘next generation’ alternative to stainless steel classical bioreactors
• Higher yield
• Better productivity
• Reduced shear stress
• Superior oxygenation